陆杰

发布时间：2019-03-12浏览次数：21762

姓    名

陆杰(Lu Jie)  教授 / 博士生导师

办公地点

3号实训楼3411

办公电话

15800851286

电子邮箱

lujie@sues.edu.cn

毕业学校

天津大学

研究方向

1. 手性结晶、生物结晶、药物结晶、工业结晶

2. 纳米晶体功能材料

3. 选择性分离与化工系统工程

4. 资源与环境化工

个人简历

2014/01 - 至今, 上海工程技术大学, 化学化工学院, 教授

2009/03-2014/01, 江南大学, 粮食发酵工艺与技术国家工程实验室, 教授


代表性项目

1. 上海市自然科学基金面上项目（25ZR1401151)“结晶拆分过程及其强化的多尺度机制研究”(2025/07-2028/06)

2. 国家自然科学基金重大研究计划项目（培育）(92156020)“药物分子晶体组装的手性传递及其调控机制研究”(2022/01-2024/12)

3. 国家自然科学基金面上项目(22078191)“纳米纤维素凝胶中药物多晶型形成机理研究”(2021/01-2024/12)

4. 国家自然科学基金国际(地区)合作交流项目(22081340412)“中韩功能产品智能化与智慧生产管理”(2020/02-2021/12)

5. 国家自然科学基金面上项目(21978165)“模板介导药物纳米晶体精准组装的多尺度研究”(2020/01-2023/12)

6. 国家自然科学基金面上项目(21476136)“生物胶体中晶体的自组装及转变机理研究：以胆固醇结石为例”(2015/01-2018/12)

7. 上海市科委重点支撑项目(15430501200)“药物晶体组装与调控共性关键技术开发”(2015/11-2020/12)

8. 国家自然科学基金国际(地区)合作研究项目(GZ935)“Toward Further Understanding and Higher Efficiency of Protein Crystallization”(2014/01-2017/12)

9. 江苏省科技厅，江苏省自然科学基金项目(BK20131100)“药物分子多晶型结晶的机理及控制研究”(2013/07-2016/06)

10. 江苏省环保厅，江苏省环保科研课题(2012004)“高盐度工业废水的绿色循环处理新技术及其应用”(2012/08-2014/07)

11. 国家自然科学基金面上项目(21176102)“蛋白质分子晶体的二维自组装研究”(2012/01-2015/12)

12. 国家自然科学基金面上项目(21176215)”恶臭假单胞菌扁桃酸消旋酶催化底物多样性产生机制的研究”(2012/01-2015/12)

13. 国家自然科学基金国际(地区)合作交流项目(GZ843)“Fundamentals and Cutting-Edge Technologies of Industrial Crystallization”(2012/01-2012/12)

14.国家自然科学基金青年项目(20106010)“生物大分子结晶机理及其控制结晶技术研究”(2002/01-2004/12)

 

荣誉奖项

2025 全球前2%顶尖科学家

2022 国家一流本科专业化学工程与工艺负责人

2021 全国石油和化工教育优秀教学团队负责人

2018 上海市科技进步二等奖（20184107-2-R01）

2015 志宏学者

2013 中国轻工业联合会科技进步三等级（2013-J-3-28-R01）

2013 中国商业联合会科技进步一等奖（2013-1-23-R01）

2010 中国轻工业联合会科技进步三等级（2010-J-3-69-R04）

2001 教育部“高等学校骨干教师”


社会兼职

委员：中国化工学会第1届医药化工专业委员会、中国药学会药物晶体工程小组、ACS等

编辑：Journal of Chemical Research and Application，American Journal of Chemical Engineering，Current Chinese Science等

评审：

       国家科技奖励初评(会评)（2025-)

       科技部各类专项与研发计划（2022-）

       上海市生态环境应急管理(2021-)

       国家科技奖励函评(2020-)

       上海等省市科技奖励函评(2019-)

上海市学位与研究生教育(2015-)

教育部博士点基金及学位与研究生教育(2013-)

中国国家基金委各类项目(2012-)等

代表性论著（论文、著作、专利）

1. Yu-Xun Tao#, Yue Xu#, Yi-Ni Wang, Yin-Xin Yang, Xiao-Xuan Wang, Ruo-Xi Huang, Lin-Xu Dong, Ruo-Xin Wen, Liang Shu, Ru-Hua Liu, Xi-Jian Liu, Jie Lu*. Crystallization resolution of a racemic compound (R,S)-sulpiride promoted by chiral ionic liquids: insight into the effect on selective nucleation. Crystal Growth & Design, 2025, 25(9), 2913−2923.

2. Yin-Xin Yang, Jie Lu*. Cocrystal technology in the screening of pharmaceutical solid forms and chiral resolution of drugs: a review. Crystal Research and Technology, 2025, 60(9), e70013.

3. Xin-Yi Chen, Hai-Kuan Yuan*, Jiang-Huan Shi, Min Zhu, Jie Lu*. PFSA-g-ZIF-L/CS-PVA mixed-matrix membrane for pervaporation desalination. Separation and Purification Technology, 2025, 357, 130128.

4. 王依妮, 陆杰*. 药物分子的溶解度预测研究进展. 化学工程, 2025, 53(9), 46−52.

5. Ya-Di Zhang, Hai-Kuan Yuan*, Xin-Yi Chen, Zhen-Lin Jiang, Jie Lu*. Incorporating MXene@MOF-303 composites into poly(vinyl alcohol) (PVA) to fabricate pervaporation membranes for desalination. ACS Applied Polymer Materials, 2024, 6(14), 8277−8290.

6. Xiao-Lan Qin#, Yue Xu#, Bo-Xuan Lou, Chang Liu, Li-Juan Zhang, Xi-Jian Liu, Hai-Kuan Yuan, Yan Zhang, Jie Lu*. Enhanced direct crystallization resolution of racemates mediated in chiral ionic liquid cosolvent mixtures: experimental, statistical, and QM simulation studies. Crystal Growth & Design, 2023, 23(6), 4607−4620.

7. Lei-Lei Zhang#, Yue Xu#, Bo-Xuan Lou, Xiao-Lan Qin, Li-Juan Zhang, Xi-Jian Liu, Hai-Kuan Yuan, Yan Zhang, Sohrab Rohani, Jie Lu*. Effect of additives on preferential crystallization for the chiral resolution of citrulline: experimental, statistical, and molecular dynamics simulation studies. Crystal Growth & Design, 2022, 22(4), 2392-2406.

8. Jiang-Hao Zhang#, Bo-Xuan Lou#, Xiao-Lan Qin, Yin-Wen Li, Hai-Kuan Yuan, Li-Juan Zhang, Xi-Jian Liu, Yan Zhang, Jie Lu*. Using amphiphilic polymer micelles as the templates of antisolvent crystallization to produce drug nanocrystals. ACS Omega, 2022, 7(24), 21000−21013.

9. Jiao-Jiao Cao#, Bo-Xuan Lou#, Yue Xu#, Xiao-Lan Qin, Hai-Kuan Yuan, Li-Juan Zhang, Yan Zhang, Sohrab Rohani, Jie Lu*. Direct crystallization resolution of racemates enhanced by chiral nanorods: experimental, statistical, and quantum mechanics/molecular dynamics simulation studies. ACS Omega, 2022, 7(23), 19828−19841.

10. 王东博, 张蕾蕾, 翟晶焕, 张丽娟, 刘锡建, 朱雪焱, 陆杰*. 青霉胺结晶热力学及拆分工艺研究. 化工学报, 2021, 72(4), 1885-1894.

11. Ran-Ran Sun, Xiao-Meng Guo, Da-Wei Yang, Ya-Lin Tang, Jie Lu*, Hong-Xia Sun*. c-Myc G-quadruplex is sensitively and specifically recognized by a fluorescent probe. Talanta, 2021, 226, 122125.

12. Dong-Bo Wang, Jie Lu*, Lei-Lei Zhang, Fan-Fan Fan, Li-Juan Zhang, Xi-Jian Liu, Hai-Kuan Yuan, Xue-Yan Zhu. Experimental and molecular dynamics simulation study on the primary nucleation of penicillamine racemate and its enantiomers in the mixture solvent of water and ethanol. Industrial & Engineering Chemistry Research, 2020, 59(50), 21957−21968.

13. Xiao-Di Liu#, Hai-Kuan Yuan#*, Cheng-Cong Wang, Shuai Zhang, Li-Juan Zhang, Xi-Jian Liu, Feng-Jiao Liu, Xue-Yan Zhu, Sohrab Rohani, Chi-Bun Ching, Jie Lu*. A novel PVDF/PFSA-g-GO ultrafiltration membrane with enhanced permeation and antifouling performances. Separation and Purification Technology, 2020, 233, 116038.

14. Min-Yi Zhang#, Xi-Jian Liu#*, Qian Luo#, Qi Wang, Lin-Jing Zhao, Guo-Ying Deng, Ren-Bin Ge, Lei Zhang*, Jun-Qing Hu, Jie Lu*. Tumor environment responsive degradable CuS@mSiO2@MnO2/DOX for MRI guided synergistic chemo-photothermal therapy and chemodynamic therapy. Chemical Engineering Journal, 2020, 124450.

15. Fan-Fan Fan#, Hai-Kuan Yuan#, Yong-Hao Feng, Feng-Jiao Liu, Li-Juan Zhang, Xi-Jian Liu, Xue-Yan Zhu, Wei An, Sohrab Rohani, Jie Lu*. Molecular simulation approaches for the prediction of unknown crystal structures and solubilities of (R)- and (R,S)-crizotinib in organic solvents. Crystal Growth & Design, 2019, 19(10), 5882−5895.

16. Lan-Fang Ren#, Xi-Jian Liu#*, Tao Ji, Guo-Ying Deng, Feng-Jiao Liu, Hai-Kuan Yuan, Jing Yu, Junqing Hu, Jie Lu*. “All-in-one” theranostic agent with seven functions based on Bi-doped metal chalcogenides nanoflowers. ACS Applied Materials & Interfaces, 2019, 11(49), 45467−45478.

18. Xue-Xue Fan, Ya-Nan Xu, Tian-Du Sheng, Dong-Qing Zhao, Hai-Kuan Yuan, Feng-Jiao Liu, Xi-Jian Liu, Xue-Yan Zhu, Li-Juan Zhang*, Jie Lu*. Amperometric sensor for dopamine based on surface-graphenization pencil graphite electrode prepared by in-situ electrochemical delamination. Microchimica Acta, 2019, 186, 324.

19. Shu-Ping Wu, Fan Wang, Hai-Kuan Yuan*, Li-Juan Zhang, Shi-Min Mao, Xi-Jian Liu, Njud S. Alharbi, Sohrab Rohani, Jie Lu*. Fabrication of xanthate-modified chitosan/poly(N-isopropylacrylamide) composite hydrogel for the selective adsorption of Cu(II), Pb(II) and Ni(II) metal ions. Chemical Engineering Research and Design, 2018, 139, 197−210.

20. Ye-Ying Wang, Xi-Jian Liu*, Guo-Ying Deng, Jian Sun, Hai-Kuan Yuan, Qi Li, Qiu-Gen Wang, Jie Lu*. Se@SiO2-FA-CuS nanocomposites for targeted delivery of DOX and nano selenium in synergistic combination of chemo-photothermal therapy. Nanoscale, 2018, 10, 2866−2875.

21. Fan Wang, Li-Juan Zhang*, Ye-Ying Wang, Xi-Jian Liu, Sohrab Rohani, Jie Lu*. Fe3O4@SiO2@CS-TETA functionalized graphene oxide for the adsorption of methylene blue (MB) and Cu (II). Applied Surface Science, 2017, 420, 970−981.

22. Ye-Ying Wang, Xi-Jian Liu*, Guo-Ying Deng, Qian Wang, Li-Juan Zhang, Qiu-Gen Wang, Jie Lu*. Multifunctional PS@CS@Au–Fe3O4–FA nanocomposites for CT, MR and fluorescence imaging guided targeted-photothermal therapy of cancer cells. Journal of Material Chemistry B, 2017, 5, 4221−4232.

23. Zhen-Xuan Fang, Xi-Jian Liu*, Mu-Dan Zhang, Jin-Rong Sun, Shi-Min Mao, Jie Lu*, Sohrab Rohani. A neural network approach to simulating the dynamic extraction process of L-phenylalanine from sodium chloride aqueous solutions by emulsion liquid membrane. Chemical Engineering Research and Design, 2016, 105, 188-199.

24. Jin-Rong Sun, Li-Juan Zhang, Shi-Min Mao, Sohrab Rohani, Jie Lu*. Solid-liquid equilibrium of NaCl + HOCH2COONa + H2O system from (283.15 to 353.15) K. Fluid Phase Equilibria, 2016, 409, 334−340.

25. Guan Liu, Li-Juan Zhang*, Shi-Min Mao, Sohrab Rohani, Chi-Bun Ching, Jie Lu*. Zwitterionic chitosan-silica-PVA hybrid ultrafiltration membranes for protein separation. Separation and Purification Technology, 2015, 152, 55−63.